Bacterial protein synthesis as a target for antibiotic inhibition

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Bacterial Protein Synthesis as a Target for Antibiotic Inhibition。

2016年9月1日 · Protein synthesis occurs on macromolecular machines, called ribosomes. Bacterial ribosomes and the translational machinery represent one of ...： 。

Bacterial Protein Synthesis as a Target for Antibiotic Inhibition - NCBI。

Therefore, studies into antibiotic action during translation provide not only insight into the inhibitory action of the antibiotics, but also insight into ...： 。

Discovery and Analysis of 4H-Pyridopyrimidines, a Class of ...。

Bacterial protein synthesis is the target for numerous natural and synthetic ... These compounds inhibited the growth of E. coli, Staphylococcus aureus, ...。

Bacterial Targets of Antibiotics in Methicillin-Resistant ... - MDPI。

Antibiotics can inhibit the growth of bacteria by targeting their cell wall, cell membrane, DNA replication, RNA synthesis, or ribosomes (protein synthesis), ...。

Mechanistic insights into translation inhibition by aminoglycoside ...。

2021年6月14日 · Many antibiotics inhibit protein synthesis in bacteria by binding in ... An anion-exchange chromatography Mono-Q GL column (GE Healthcare) ...。

Translational control of antibiotic resistance | Open Biology。

2019年7月10日 · When a bacterial pathogen is treated with a translation inhibitor, ... of common translation drug targets, mechanisms of resistance, ...。

How antibiotics kill bacteria: from targets to networks - Nature。

2010年5月4日 · Most current bactericidal antimicrobials — which are the focus of this Review — inhibit DNA, RNA, cell wall or protein synthesis. Since the ...。

A novel site of antibiotic action in the ribosome: Interaction of ... - PNAS。

2001年3月27日 · Resistance mutations in the bacterial ribosomal protein L16, ... number of natural and synthetic antibiotics inhibit protein synthesis.。

Molecular mechanism of viomycin inhibition of peptide elongation in ...。

2016年1月26日 · The tuberactinomycin antibiotics are bacterial protein synthesis inhibitors, commonly used as second-line drugs against multidrug-resistant ...。

Full article: Drugging tRNA aminoacylation - Taylor & Francis Online。

Inhibition of tRNA aminoacylation has proven to be an effective antimicrobial strategy, impeding an essential step of protein synthesis.

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